Virulence factors of non-Candida albicans Candida species
ثبت نشده
چکیده
Candidosis caused by non-Candida albicans Candida (NCAC) species have been increased in recent years, namely due Candida glabrata, Candida tropicalis and Candida parapsilosis. Furthermore, candidosis is facilitated by a number of virulence factors, such as adherence to medical devices and/or host cells, biofilm formation and secretion of enzymes. Thus, the main goal of this study was to characterize clinical isolates of C. glabrata, C. tropicalis and C. parapsilosis recovered from different body sites (oral cavity and urinary and vaginal tracts).in terms of the most important virulence factors (adhesion, biofilm formation ability, tissue colonization and invasion, and expression of secreted aspartly proteinases).
منابع مشابه
The Evaluation of the virulence factors of clinical Candida isolates and the anti-biofilm activity of Elettaria cardamomum against multi-drug resistant Candida albicans
Background and Purpose: Today, treatment of life-threatening fungal infections, caused by Candida species, has become a major problem. In the present study, we aimed to evaluate the antifungal susceptibility patterns of different clinical Candida isolates, determine the virulence factors in multi-drug resistant (MDR) Candida species, and assess the anti-biofilm activity of Elettaria cardamomum ...
متن کاملEvaluation of esterase and hemolysin activities of different Candida species isolated from vulvovaginitis cases in Lorestan Province, Iran
Background and Purpose: Annually affecting millions of women, vulvovaginal candidiasis (VVC) is commonly described by signs and symptoms of vulvovaginal inflammation in the presence of Candida species. Today, the detection of the virulence factors plays a major role in the understanding of pathogenesis of candidiasis and helps produce new anticandidial drugs to improve its treatment efficiency....
متن کاملNon-albicans Candida Infection: An Emerging Threat
The very nature of infectious diseases has undergone profound changes in the past few decades. Fungi once considered as nonpathogenic or less virulent are now recognized as a primary cause of morbidity and mortality in immunocompromised and severely ill patients. Candida spp. are among the most common fungal pathogens. Candida albicans was the predominant cause of candidiasis. However, a shift ...
متن کاملCandida species adhesion to oral epithelium: factors involved and experimental methodology used.
Due to the increasing prevalence and emergence of Non-Candida albicans Candida (NCAC) species, especially in immunosupressed patients, it is becoming urgent to deepen the current knowledge about virulence factors of these species. Adhesion of cells to epithelium is considered one of the major virulence factors of Candida species. However, relatively little is known concerning the adhesion mecha...
متن کاملComparison Between Virulence Factors of Candida albicans and Non-Albicans Species of Candida Isolated from Genitourinary Tract.
BACKGROUND Candida spp. is frequently isolated from cases of vulvovaginal candidiasis and catheter associated UTI. C.albicans is the most frequently isolated species but non-albicans species of candida are gaining clinical significance. OBJECTIVES To compare the virulence factors like biofilm production, phospholipase and hemolytic activity in C.albicans with that of non albicans species of c...
متن کامل